SCHEMBL7315427

SCHEMBL7315427

COc1ccc(-c2cc(=O)c3c(O)cc(OCC(=O)OC(C)(C)C)cc3o2)cc1OC(C)CCCc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.62
LMNA P02545 1/20 0.62
POLB P06746 1/20 0.54
CYP2C9 P11712 1/20 0.54
HPGD P15428 1/20 0.54
CYP2C19 P33261 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
KDM5A P29375 1/20 0.51
PPARG P37231 1/20 0.51
PDE4A P27815 3/20 0.49
PDE4B Q07343 3/20 0.49
PDE4C Q08493 3/20 0.49
PDE4D Q08499 3/20 0.49
CYP1B1 Q16678 1/20 0.47
EGFR P00533 10/20 0.47
ABL1 P00519 1/20 0.46
ABCB1 P08183 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7307667 0.91 PPARG (0.55) MAPTLMNAPOLBCYP2C9CYP2C19
SCHEMBL7306215 0.91 KDM5A (0.55) MAPTLMNAPOLBCYP2C9HPGD
SCHEMBL7304890 0.91 PPARG (0.53) MAPTLMNAKDM5APPARGPDE4A
SCHEMBL7307211 0.90 PDE4A (0.54) MAPTLMNAPOLBCYP2C9CYP2C19
SCHEMBL7314642 0.90 PPARG (0.54) MAPTLMNAPOLBCYP2C9CYP2C19
SCHEMBL7306656 0.89 NPSR1 (0.59) MAPTLMNAPOLBNPSR1KDM5A
SCHEMBL7317638 0.88 PPARG (0.58) PPARGPDE4APDE4BPDE4CPDE4D
SCHEMBL7307612 0.88 PPARG (0.58) KDM5APPARGPDE4APDE4BPDE4C
SCHEMBL7307218 0.88 PPARG (0.52) MAPTLMNAPOLBNPSR1KDM5A
SCHEMBL7315470 0.88 PPARG (0.51) MAPTKDM5APPARGPDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103619749-B Connector for actuating a delivery tap VITOP MOULDING S.R.L. (IT) 2015-09-30 CN disclosed
CN-103619749-A Connector for actuating a delivery tap VITOP MOULDING SRL 2014-03-05 CN disclosed
EP-0832886-B1 Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them SERVIER LAB (FR) 2002-11-13 EP disclosed
US-5934083-A Air-conditioning system for an aircraft cabin DAIMLERCHRYSLER AEROSPACE AIRBUS GMBH (DE) 1999-08-10 US disclosed
EP-0832886-A1 Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1998-04-01 EP disclosed
US-H713-H Automatic target detection and recognition THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1989-11-07 US disclosed