Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.69 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.69 |
| ▸ | SUCNR1 | Q9BXA5 | 7/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327782 | 1.00 | ITGB3 (0.69) | ITGB3ITGA2BSUCNR1ITGB1ITGA4 | |
| SCHEMBL7300050 | 0.90 | ITGB3 (0.61) | ITGB3ITGA2BSUCNR1ACE | |
| SCHEMBL7298204 | 0.90 | ITGB3 (0.61) | ITGB3ITGA2BSUCNR1ACE | |
| SCHEMBL7319944 | 0.87 | ITGB3 (0.67) | ITGB3ITGA2BSUCNR1CA12CA1 | |
| SCHEMBL7352113 | 0.86 | ITGB3 (0.66) | ITGB3ITGA2BSUCNR1CA12CA1 | |
| SCHEMBL7330647 | 0.86 | ITGB3 (0.74) | ITGB3ITGA2BITGB1ITGA4ACE | |
| SCHEMBL7335757 | 0.86 | ITGB3 (0.74) | ITGB3ITGA2BITGB1ITGA4ACE | |
| SCHEMBL13726312 | 0.85 | ITGB3 (0.65) | ITGB3ITGA2BSUCNR1CA12CA1 | |
| SCHEMBL6369971 | 0.85 | ACE (0.67) | ACE | |
| SCHEMBL7300004 | 0.85 | ITGB3 (0.64) | ITGB3ITGA2BSUCNR1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478328-B1 | Novel fibrinogen receptor antagonists | MERCK & CO INC (US) | 1996-01-10 | — | — | EP | disclosed |
| US-5294616-A | Anticoagulants, inhibition of fibrinogen binding to blood platelets | MERCK & CO., INC. (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0478328-A1 | Novel fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-04-01 | — | — | EP | disclosed |