Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316770 | 0.81 | PDK2 (0.43) | OPRM1OPRL1OPRD1OPRK1CHRM2 | |
| SCHEMBL7319059 | 0.76 | CHRM2 (0.42) | PKMOPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL28229665 | 0.71 | HCAR2 (0.38) | KDM4EOPRM1OPRL1MEN1KMT2A | |
| Methane SCHEMBL28321651 | 0.70 | HCAR2 (0.37) | OPRM1OPRL1 | |
| SCHEMBL7322102 | 0.70 | P2RX1 (0.46) | KDM4EPKMPDK2GAAMAPT | |
| SCHEMBL7316176 | 0.69 | PDK2 (0.50) | PDK2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL24281886 | 0.69 | KMT2A (0.57) | KDM4ECHRM2PDK2MEN1KMT2A | |
| SCHEMBL7320725 | 0.68 | PDK2 (0.51) | PDK2 | |
| SCHEMBL10490974 | 0.68 | MAPT (0.44) | KDM4EPDK2MEN1KMT2AALDH1A1 | |
| SCHEMBL7315243 | 0.66 | PDK2 (0.41) | PDK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |