Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 13/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316770 | 0.86 | PDK2 (0.43) | PDK2ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL7315243 | 0.82 | PDK2 (0.41) | PDK2ALDH1A1L3MBTL1NFKB1NFKB2 | |
| SCHEMBL7322740 | 0.82 | PDK2 (0.53) | PDK2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL7323011 | 0.82 | PDK2 (0.53) | PDK2MEN1KMT2ALMNAMAPT | |
| SCHEMBL7320725 | 0.81 | PDK2 (0.51) | PDK2 | |
| SCHEMBL7314066 | 0.76 | PDK2 (0.57) | PDK2ALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL13326301 | 0.76 | PDK2 (0.38) | PDK2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL16167864 | 0.75 | PDK2 (0.37) | PDK2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL14227873 | 0.75 | PDK2 (0.55) | PDK2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL14182746 | 0.75 | PDK2 (0.55) | PDK2ALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |