Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CSK | P41240 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315674 | 0.85 | SRC (0.39) | SRCAKT1FYNRIPK2PRKD3 | |
| SCHEMBL7312284 | 0.75 | HPGD (0.49) | SRCAKT1FYNRIPK2PRKD3 | |
| SCHEMBL13063870 | 0.75 | SRC (0.67) | SRCAKT1FYNRIPK2PRKD3 | |
| SCHEMBL7320063 | 0.70 | EGFR (0.39) | SRCABL1ALDH1A1HSD17B10PRKCI | |
| SCHEMBL13063872 | 0.63 | SRC (0.66) | SRCAKT1FYNRIPK2PRKD3 | |
| SCHEMBL7319854 | 0.63 | RIPK2 (0.45) | SRCRIPK2CYP1A2CYP3A4 | |
| SCHEMBL13019709 | 0.62 | SRC (0.73) | SRCAKT1FYNRIPK2PRKD3 | |
| SCHEMBL3785884 | 0.62 | SRC (0.74) | SRCAKT1FYNRIPK2PRKD3 | |
| SCHEMBL1960756 | 0.61 | SRC (0.69) | SRCAKT1FYNRIPK2PRKD3 | |
| SCHEMBL1961935 | 0.61 | SRC (0.62) | SRCAKT1FYNRIPK2PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541187-A | HYPOTENSIVE AGENTS | STERLING WINTHROP INC. (US) | 1996-07-30 | — | — | US | disclosed |
| US-5294612-A | Hypotensive agents and cardiovascular disorders | STERLING WINTHROP INC. (US) | 1994-03-15 | — | — | US | disclosed |