Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 8/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 4/20 | 0.37 |
| ▸ | BIRC3 | Q13489 | 4/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308389 | 0.89 | TACR1 (0.42) | TACR1CFDDPP8DPP7XIAP | |
| SCHEMBL7318712 | 0.88 | DPP8 (0.43) | TACR1CFDDPP8DPP7DPP4 | |
| SCHEMBL7304910 | 0.85 | F2 (0.40) | TACR1CFDDPP8DPP7XIAP | |
| SCHEMBL7317505 | 0.83 | TACR1 (0.41) | TACR1CFDDPP8DPP7DPP4 | |
| SCHEMBL7316930 | 0.80 | TACR1 (0.42) | TACR1CFDDPP8DPP7XIAP | |
| SCHEMBL7315075 | 0.80 | TACR1 (0.43) | TACR1CFDDPP8DPP7DPP4 | |
| SCHEMBL7308390 | 0.80 | TACR1 (0.44) | TACR1CFDDPP8DPP7DPP4 | |
| SCHEMBL8083547 | 0.80 | TACR1 (0.44) | TACR1CFDDPP8DPP7DPP4 | |
| SCHEMBL7308379 | 0.80 | TACR1 (0.44) | TACR1CFDDPP8DPP7DPP4 | |
| SCHEMBL7316941 | 0.77 | DPP8 (0.41) | TACR1CFDDPP8DPP7XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |