Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.41 |
| ▸ | KLK1 | P06870 | 6/20 | 0.41 |
| ▸ | F2 | P00734 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ACR | P10323 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.36 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.36 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.36 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1646119 | 0.87 | KMT2A (0.43) | PRSS1KLK1F2KMT2AACR | |
| SCHEMBL1399030 | 0.86 | PRSS1 (0.42) | PRSS1KLK1F2KMT2AACR | |
| SCHEMBL1399027 | 0.82 | PRSS1 (0.43) | PRSS1KLK1F2KMT2AACR | |
| SCHEMBL1399029 | 0.80 | KMT2A (0.44) | PRSS1KLK1F2KMT2AACR | |
| SCHEMBL7315839 | 0.79 | PRSS1 (0.46) | PRSS1KLK1F2KMT2AACR | |
| SCHEMBL11417283 | 0.78 | PRSS1 (0.50) | PRSS1KLK1F2KMT2AACR | |
| SCHEMBL11305433 | 0.78 | PRSS1 (0.41) | PRSS1KLK1F2KMT2AACR | |
| SCHEMBL9235641 | 0.78 | PRSS1 (0.51) | PRSS1KLK1F2KMT2AACR | |
| SCHEMBL9232530 | 0.78 | PRSS1 (0.51) | PRSS1KLK1F2KMT2AACR | |
| SCHEMBL11305428 | 0.78 | PRSS1 (0.56) | PRSS1KLK1F2KMT2AACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021472-A | ANTIPLASMIN AND ANTITRYPSIN | ONO PHARMACEUTICAL CO., LTD. (JA) | 1977-05-03 | — | — | US | disclosed |