Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322751 | 1.00 | KDM4E (0.43) | KDM4ERAB9ANPC1SMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL7320537 | 0.99 | KDM4E (0.43) | KDM4ERAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL7322038 | 0.99 | KDM4E (0.44) | KDM4ERAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL7349840 | 0.92 | KDM4E (0.45) | KDM4ERAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL7322947 | 0.91 | KDM4E (0.42) | KDM4ERAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL7312609 | 0.91 | KDM4E (0.42) | KDM4ERAB9ANPC1SMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL7322342 | 0.91 | KDM4E (0.44) | KDM4ERAB9ANPC1SMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL7322012 | 0.90 | KDM4E (0.41) | KDM4ERAB9ANPC1SMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL7324434 | 0.90 | KDM4E (0.41) | KDM4ERAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL7325009 | 0.73 | KDM4E (0.41) | KDM4ERAB9ANPC1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719145-A | FIBRINOGEN ANTAGONIST FOR TREATMENT OF THROMBOSIS, RESTENOSIS AFTER ANGIOPLASTY OR CORONARY RECANALIZATION; WATER SOLUBILITY, ORAL ADMINISTRATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-02-17 | — | — | US | disclosed |