Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355860 | 0.92 | RAB9A (0.43) | KDM4ERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7319815 | 0.91 | KDM4E (0.40) | KDM4ERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7319158 | 0.91 | KDM4E (0.40) | KDM4ERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7322830 | 0.90 | KDM4E (0.39) | KDM4ERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7322751 | 0.73 | KDM4E (0.43) | KDM4ERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7315913 | 0.73 | KDM4E (0.43) | KDM4ERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7320537 | 0.72 | KDM4E (0.43) | KDM4ERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7322038 | 0.72 | KDM4E (0.44) | KDM4ERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7315917 | 0.66 | SMN1; SMN2 (0.39) | KDM4ERAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7320541 | 0.66 | SMN1; SMN2 (0.39) | KDM4ERAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719145-A | FIBRINOGEN ANTAGONIST FOR TREATMENT OF THROMBOSIS, RESTENOSIS AFTER ANGIOPLASTY OR CORONARY RECANALIZATION; WATER SOLUBILITY, ORAL ADMINISTRATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-02-17 | — | — | US | disclosed |