Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 4/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.32 |
| ▸ | MAPT | P10636 | 7/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318853 | 0.84 | PDE3B (0.51) | PDE3BPDE3A | |
| SCHEMBL7316075 | 0.83 | PDE3B (0.49) | PDE3BPDE3ATSHRGAAALDH1A1 | |
| SCHEMBL7307453 | 0.83 | PDE3B (0.52) | PDE3BPDE3A | |
| SCHEMBL7317200 | 0.79 | PDE3B (0.50) | PDE3BPDE3ATSHRALDH1A1MAPT | |
| SCHEMBL7319841 | 0.78 | PDE3B (0.48) | PDE3BPDE3A | |
| SCHEMBL7317001 | 0.77 | MAPT (0.31) | ALDH1A1MAPTPOLB | |
| SCHEMBL7316084 | 0.75 | PDE3B (0.56) | PDE3BPDE3A | |
| SCHEMBL7320840 | 0.71 | PDE3B (0.49) | PDE3BPDE3A | |
| SCHEMBL7318831 | 0.70 | PDE3B (0.56) | PDE3BPDE3A | |
| SCHEMBL11983676 | 0.69 | PDE3B (0.55) | PDE3BPDE3AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |