Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 17/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 17/20 | 0.51 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307453 | 0.99 | PDE3B (0.52) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7316094 | 0.84 | PDE3B (0.45) | PDE3BPDE3A | |
| SCHEMBL7318831 | 0.81 | PDE3B (0.56) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7307441 | 0.81 | PDE3B (0.57) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7309048 | 0.75 | PDE3B (0.54) | PDE3BPDE3AP2RY12 | |
| SCHEMBL7318841 | 0.75 | PDE3B (0.65) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7312202 | 0.74 | PDE3B (0.55) | PDE3BPDE3A | |
| SCHEMBL7317200 | 0.71 | PDE3B (0.50) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL11983524 | 0.69 | PDE3B (0.49) | PDE3BPDE3A | |
| SCHEMBL7313147 | 0.69 | PDE3B (0.86) | PDE3BPDE3AP2RY12PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |