Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390921 | 0.82 | HTT (0.41) | MAPTPOLBSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL25433738 | 0.80 | MAPT (0.50) | MAPTPOLBSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL28406778 | 0.78 | PIK3CA (0.46) | MAPTPOLBPTGS1NPY5R | |
| SCHEMBL7326746 | 0.77 | MAPT (0.45) | MAPTPOLBSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL14132597 | 0.77 | ADORA2A (0.54) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL7318896 | 0.76 | MAPT (0.47) | MAPTPOLBSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL15610305 | 0.75 | MAPT (0.45) | MAPTSMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL11449832 | 0.73 | MAPT (0.72) | MAPTPOLBSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL7328574 | 0.72 | MAPT (0.46) | MAPTPOLBSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL7325706 | 0.72 | MAPT (0.43) | MAPTPOLBSMN1; SMN2PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES | 2001-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | IL5, IL2, IL4 | MAPT 2674/4885POLB 4430/4885SMN1; SMN2 4665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.