Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083051 | 0.90 | ACE (0.45) | ACE | |
| SCHEMBL10920023 | 0.87 | ACE (0.70) | ACE | |
| SCHEMBL7323422 | 0.87 | ACE (0.54) | ACE | |
| SCHEMBL11075229 | 0.84 | ACE (0.51) | ACE | |
| SCHEMBL7316482 | 0.83 | ACE (0.37) | ACE | |
| SCHEMBL11196761 | 0.83 | ACE (0.75) | ACE | |
| SCHEMBL828672 | 0.83 | ACE (0.75) | ACE | |
| SCHEMBL5563136 | 0.83 | ACE (0.48) | ACE | |
| SCHEMBL5563133 | 0.83 | ACE (0.48) | ACE | |
| Water SCHEMBL11075523 | 0.82 | ACE (0.73) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050850-A1 | 1-Carboxyalkanoylindolin-2-carboxylic acids and derivatives thereof, processes for their preparation, and pharmaceutical compositions containing these compounds | CIBA-GEIGY AG (CH) | 1982-05-05 | — | — | EP | disclosed |