Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.39 |
| ▸ | FNTB | P49356 | 2/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313580 | 0.92 | FNTA (0.39) | FNTAFNTBPGGT1BCYP3A4CTSS | |
| SCHEMBL7312048 | 0.92 | FNTA (0.39) | FNTAFNTBPGGT1BCYP3A4CTSS | |
| SCHEMBL7316235 | 0.92 | FNTA (0.39) | FNTAFNTBPGGT1BCYP3A4CTSS | |
| SCHEMBL7314588 | 0.90 | CACNA1B (0.38) | FNTAFNTBPGGT1BCACNA1BCTSS | |
| SCHEMBL7306029 | 0.89 | FNTA (0.36) | FNTAFNTBPGGT1BCYP3A4CTSS | |
| SCHEMBL7313466 | 0.85 | FNTA (0.39) | FNTAFNTBPGGT1BCYP3A4CTSS | |
| SCHEMBL7307016 | 0.85 | EPHX2 (0.36) | FNTAFNTBPGGT1BCTSSCTSK | |
| SCHEMBL7316023 | 0.82 | FNTA (0.43) | FNTAFNTBPGGT1BCNR1CNR2 | |
| SCHEMBL7307986 | 0.81 | FNTA (0.42) | FNTAFNTBPGGT1BCNR1CNR2 | |
| SCHEMBL7304422 | 0.80 | CTSL (0.50) | CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |