Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313154 | 0.81 | ALDH1A1 (0.43) | ALDH1A1PKMMEN1KMT2ALMNA | |
| SCHEMBL7316819 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TSHRCNR2PKMMEN1 | |
| SCHEMBL15546987 | 0.65 | CNR2 (0.64) | CNR2PKMLMNACA12CA1 | |
| SCHEMBL8773510 | 0.65 | CNR2 (0.64) | CNR2PKMLMNACA12CA1 | |
| SCHEMBL13911366 | 0.64 | MEN1 (0.72) | ALDH1A1TSHRCNR2MEN1KMT2A | |
| SCHEMBL3418990 | 0.64 | CNR2 (0.60) | CNR2PKMLMNACA12CA1 | |
| SCHEMBL2187595 | 0.63 | CNR2 (0.59) | CNR2PKMLMNACA12CA1 | |
| SCHEMBL28042133 | 0.62 | CNR2 (0.61) | CNR2PKMLMNACA12CA1 | |
| SCHEMBL8721454 | 0.62 | MEN1 (0.68) | ALDH1A1TSHRCNR2PKMMEN1 | |
| SCHEMBL31657256 | 0.62 | CNR2 (0.54) | CNR2PKMLMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280956-B1 | THIAZOLIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| EP-0280956-A1 | Thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | claimed |