Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311180 | 0.88 | PDE3B (0.47) | MAOBNPC1RAB9APDE3BPDE3A | |
| SCHEMBL7318596 | 0.85 | NPC1 (0.43) | NPC1RAB9APDE3BPDE3APKM | |
| SCHEMBL10374643 | 0.85 | NPC1 (0.43) | NPC1RAB9APDE3BPDE3APKM | |
| SCHEMBL7314387 | 0.85 | PDE3B (0.42) | MAOBNPC1RAB9APDE3BPDE3A | |
| SCHEMBL7310331 | 0.85 | PKM (0.43) | NPC1RAB9APDE3BPDE3APKM | |
| SCHEMBL10375855 | 0.83 | NPC1 (0.43) | NPC1RAB9APDE3BPDE3APKM | |
| SCHEMBL7309403 | 0.83 | KMT2A (0.47) | NPC1RAB9APDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL10374758 | 0.82 | NPC1 (0.44) | NPC1RAB9APDE3BPDE3APKM | |
| SCHEMBL10377086 | 0.81 | PDE3B (0.46) | NPC1RAB9APDE3BPDE3APKM | |
| SCHEMBL7304356 | 0.79 | PDE3B (0.46) | NPC1RAB9APDE3BPDE3APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |