Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9667284 | 0.93 | ALDH1A1 (0.52) | BCHEACHEALDH1A1MEN1KMT2A | |
| SCHEMBL2371999 | 0.86 | BCHE (0.60) | BCHEACHEALDH1A1MEN1KMT2A | |
| SCHEMBL9585091 | 0.83 | MAPK1 (0.52) | BCHEACHEALDH1A1MEN1KMT2A | |
| SCHEMBL6341381 | 0.82 | ALDH1A1 (0.63) | BCHEACHEALDH1A1 | |
| SCHEMBL7315279 | 0.79 | CYP1A2 (0.39) | BCHEACHEALDH1A1KMT2A | |
| SCHEMBL6778910 | 0.78 | MAPT (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9584471 | 0.77 | ABCC3 (0.46) | BCHEACHEALDH1A1MEN1KMT2A | |
| SCHEMBL9585054 | 0.77 | MAPK1 (0.43) | BCHEACHEALDH1A1MEN1KMT2A | |
| SCHEMBL26522270 | 0.77 | AKR1B1 (0.52) | ACHEALDH1A1MEN1KMT2A | |
| SCHEMBL20495062 | 0.76 | ALDH1A1 (0.58) | BCHEACHEALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31617-E | ANTICOAGULANTS; HYPOTENSIVE AND BRONCHODILATOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1984-06-26 | — | — | US | disclosed |
| US-3983120-A | HYPOTENSIVES, ANTICLOTTING | BRISTOL-MYERS COMPANY (US) | 1976-09-28 | — | — | US | disclosed |
| US-3932407-A | BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTICOAGULANTS | BRISTOL-MYERS COMPANY (US) | 1976-01-13 | — | — | US | disclosed |