Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318572 | 0.84 | RAB9A (0.57) | HRH3KDM4ENPC1ALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL7314288 | 0.84 | RAB9A (0.56) | HRH3KDM4ENPC1ALDH1A1GLA | |
| SCHEMBL10569275 | 0.82 | HRH3 (0.68) | HRH3KDM4ENPC1ALDH1A1POLB | |
| SCHEMBL7678918 | 0.81 | HRH3 (0.66) | HRH3KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL7684201 | 0.80 | HRH3 (0.67) | HRH3KDM4ENPC1ALDH1A1GAA | |
| SCHEMBL7681802 | 0.80 | HRH3 (0.67) | HRH3KDM4ENPC1ALDH1A1POLB | |
| SCHEMBL7317440 | 0.80 | HRH3 (0.70) | HRH3 | |
| SCHEMBL7319647 | 0.79 | SMN1; SMN2 (0.56) | HRH3KDM4ENPC1POLBRAB9A | |
| Hydrochloric Acid SCHEMBL7318014 | 0.79 | HRH3 (0.69) | HRH3 | |
| Hydrochloric Acid SCHEMBL7307729 | 0.78 | NPC1 (0.55) | HRH3NPC1POLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880824-A | CARDIOVASCULAR DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-11-14 | — | — | US | disclosed |