Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.63 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.63 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.63 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.63 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.63 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.63 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384786 | 0.93 | GABRA1 (0.63) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10627899 | 0.90 | GABRA1 (0.60) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10632282 | 0.90 | — | — | |
| SCHEMBL10630012 | 0.89 | GABRA1 (0.58) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7392665 | 0.88 | GABRA1 (0.58) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7391924 | 0.88 | GABRA1 (0.58) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10625344 | 0.87 | GABRA1 (0.66) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10626552 | 0.87 | — | — | |
| SCHEMBL7395810 | 0.86 | GABRA1 (0.56) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7393982 | 0.86 | GABRA1 (0.56) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109921-B1 | BENZODIAZEPINE RECEPTORS AND THEIR PREPARATION | A/S FERROSAN (DK) | 1988-03-02 | — | — | EP | claimed |
| US-4507313-A | Oxadiazolyl-imidazo-[1,4]benzodiazepines and their use in treatment of diseases of the central nervous system | A/S FERROSAN (DK) | 1985-03-26 | — | — | US | claimed |
| EP-0109921-B1 | BENZODIAZEPINE RECEPTORS AND THEIR PREPARATION | A/S FERROSAN (DK) | 1988-03-02 | — | — | EP | disclosed |
| US-4507313-A | Oxadiazolyl-imidazo-[1,4]benzodiazepines and their use in treatment of diseases of the central nervous system | A/S FERROSAN (DK) | 1985-03-26 | — | — | US | disclosed |