Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | FABP7 | O15540 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547888 | 0.85 | HTR2A (0.42) | HTR2ACA1CA2TSHRHSD17B10 | |
| SCHEMBL28923189 | 0.78 | HTR2A (0.48) | HTR2ACA1CA2TSHRHSD17B10 | |
| SCHEMBL2069077 | 0.77 | HTR2A (0.52) | HTR2ACA1CA2TSHRGPR3 | |
| SCHEMBL25817086 | 0.77 | KMT2A (0.44) | HSD17B10KMT2APOLBCYP1A2 | |
| SCHEMBL252162 | 0.77 | HTR2A (0.52) | HTR2ACA1CA2TSHRGPR3 | |
| SCHEMBL28747356 | 0.77 | HTR2A (0.52) | HTR2ACA1CA2GPR3POLB | |
| SCHEMBL12122139 | 0.77 | MAOA (0.47) | TSHRHDAC3HDAC4HDAC7HDAC8 | |
| SCHEMBL14407923 | 0.77 | HTR2A (0.57) | HTR2AHDAC4HDAC7HDAC5 | |
| SCHEMBL28492063 | 0.76 | HTR2A (0.50) | HTR2ACA1CA2TSHRGPR3 | |
| SCHEMBL21896104 | 0.75 | HTR2A (0.45) | HTR2ACA1CA2TSHRHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 564 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024089191-A1 | MICROBIOCIDAL HETEROBICYCLIC DIHYDROOXADIAZINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-05-02 | — | — | WO | claimed |
| WO-2023090935-A1 | METHOD FOR PRODUCING AGM PEPTIDES THAT BIND SPECIFICALLY TO NUCLEOLIN | 애니젠 주식회사 | 2023-05-25 | — | — | WO | claimed |
| CN-114096264-A | Process for preparing PSMA conjugates | 因多塞特股份有限公司 | 2022-02-25 | — | — | CN | claimed |
| US-11149064-B2 | Vasoactive polypeptides for smooth muscle relaxation | VANDERBILT UNIVERSITY (US) | 2021-10-19 | — | — | US | claimed |
| EP-3026049-B1 | METHOD FOR PREPARING BENZAMIDE DERIVATIVE, NOVEL INTERMEDIATE USED IN PREPARATION OF BENZAMIDE, AND METHOD FOR PREPARING NOVEL INTERMEDIATE | DONG A ST CO LTD (KR) | 2021-09-22 | — | — | EP | claimed |
| EP-3274358-B1 | VACCINE AGAINST CARBAPENEM-RESISTANTKLEBSIELLA PNEUMONIAE | MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS EV (DE) | 2020-09-16 | — | — | EP | claimed |
| CN-111499686-A | Phosphorylated protein labeling reagent containing equal-weight stable isotope, and preparation method and application thereof | 厦门大学 | 2020-08-07 | — | — | CN | claimed |
| CN-110267958-A | Process for preparing pyrazolo [1,5-a ] pyrimidines and salts thereof | 阿雷生物药品公司 | 2019-09-20 | — | — | CN | claimed |
| EP-3532475-A2 | PROCESS FOR THE PREPARATION OF PYRAZOLO[1,5-a]PYRIMIDINES AND SALTS THEREOF | Array Biopharma Inc. (US) | 2019-09-04 | — | — | EP | claimed |
| EP-3509613-A1 | VASOACTIVE POLYPEPTIDES FOR SMOOTH MUSCLE RELAXATION | Vanderbilt University (US) | 2019-07-17 | — | — | EP | claimed |
| US-5622945-A | Rubyrin macrocycles | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1997-04-22 | — | — | US | claimed |
| US-5457195-A | Sapphyrin derivatives and conjugates | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-10-10 | — | — | US | claimed |
| WO-1994009003-A1 | SAPPHYRIN DERIVATIVES, CONJUGATES AND POLYMERS THEREOF AND EXPANDED PORPHYRIN CHROMATOGRAPHIC SUPPORTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1994-04-28 | — | — | WO | claimed |
| EP-0255082-B1 | Renin-inhibiting di- and tripeptides, methods for their production, drugs containing them, and their use | HOECHST AG (DE) | 1993-12-01 | — | — | EP | claimed |
| EP-0517589-A2 | Tachykinin derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-12-09 | — | — | EP | claimed |
| EP-0394829-A1 | Renin-inhibiting dipeptides, process to synthetize them, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-31 | — | — | EP | claimed |
| US-4855286-A | HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | claimed |
| EP-0255082-A2 | Renin-inhibiting di- and tripeptides, methods for their production, drugs containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-03 | — | — | EP | claimed |
| EP-0239874-A2 | Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their application | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-10-07 | — | — | EP | claimed |
| EP-0230242-A2 | Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-29 | — | — | EP | claimed |