Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316967 | 0.91 | TSHR (0.37) | KCNQ2PDE3BPDE3APDE4APDE4B | |
| SCHEMBL7310529 | 0.90 | PDE3B (0.35) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7320125 | 0.89 | PDE4A (0.43) | KCNQ2PDE3BPDE3APDE4APDE4B | |
| SCHEMBL7311655 | 0.86 | PDE3B (0.38) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7317849 | 0.84 | PDE3B (0.35) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7316080 | 0.83 | PDE3B (0.36) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7316529 | 0.81 | PDE3B (0.35) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7318132 | 0.81 | NPC1 (0.38) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7318644 | 0.80 | PDE3B (0.35) | KCNQ2PDE3BPDE3APDE4APDE4B | |
| SCHEMBL7316957 | 0.79 | PDE3B (0.35) | KCNQ2PDE3BPDE3APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |