Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320179 | 0.92 | PDE4A (0.38) | PDE3BPDE3ATSHRPOLBL3MBTL1 | |
| SCHEMBL7317651 | 0.91 | PDE3B (0.38) | PDE3BPDE3ATSHRPOLBL3MBTL1 | |
| SCHEMBL7314019 | 0.90 | PDE3B (0.38) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7307661 | 0.89 | PDE4A (0.43) | PDE3BPDE3ATSHRPOLBL3MBTL1 | |
| SCHEMBL7317853 | 0.86 | KCNQ2 (0.39) | PDE3BPDE3ATSHRL3MBTL1PDE4A | |
| SCHEMBL7313053 | 0.81 | PDE3B (0.38) | PDE3BPDE3ATSHRPDE4APDE4B | |
| SCHEMBL7303658 | 0.81 | PDE3B (0.39) | PDE3BPDE3ATSHRPDE4APDE4B | |
| SCHEMBL7313872 | 0.81 | PDE3B (0.37) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7321069 | 0.79 | PDE4A (0.43) | PDE3BPDE3ATSHRL3MBTL1KCNA5 | |
| SCHEMBL7320482 | 0.79 | NPC1 (0.36) | PDE3BPDE3ATSHRKCNA5PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |