Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318460 | 0.91 | MAPT (0.42) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7307164 | 0.90 | MAPT (0.41) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7316028 | 0.85 | NPC1 (0.42) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7320158 | 0.84 | NPC1 (0.40) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7314882 | 0.79 | NPC1 (0.41) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7318308 | 0.76 | NPC1 (0.39) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7314556 | 0.75 | SMN1; SMN2 (0.40) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7318392 | 0.74 | SMN1; SMN2 (0.39) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7317898 | 0.71 | MAPT (0.53) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7309450 | 0.71 | MAPT (0.52) | MAPTNPC1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |