Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309728 | 0.87 | MAPK1 (0.38) | NPC1RAB9AMAPTMAPK1ALDH1A1 | |
| SCHEMBL7321025 | 0.86 | ALDH1A1 (0.39) | NPC1RAB9AMAPTMAPK1ALDH1A1 | |
| SCHEMBL7314872 | 0.81 | NPC1 (0.40) | NPC1RAB9AMAPTMAPK1ALDH1A1 | |
| SCHEMBL7318460 | 0.81 | MAPT (0.42) | NPC1RAB9AMAPTALDH1A1GAA | |
| SCHEMBL7307164 | 0.80 | MAPT (0.41) | NPC1RAB9AMAPTMAPK1ALDH1A1 | |
| SCHEMBL7317906 | 0.79 | MAPT (0.52) | NPC1RAB9AMAPTALDH1A1GAA | |
| SCHEMBL7316814 | 0.77 | NPC1 (0.42) | NPC1RAB9AMAPTMAPK1ALDH1A1 | |
| SCHEMBL7316959 | 0.73 | ALDH1A1 (0.35) | NPC1RAB9AMAPTMAPK1ALDH1A1 | |
| SCHEMBL7314876 | 0.72 | MAOB (0.44) | NPC1RAB9AMAPTMAPK1ALDH1A1 | |
| SCHEMBL7312257 | 0.69 | ALDH1A1 (0.37) | NPC1RAB9AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |