Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312230 | 0.90 | KMT2A (0.39) | PDE3BPDE3AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7314675 | 0.84 | PDE3B (0.47) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7314666 | 0.83 | PDE3B (0.40) | PDE3BPDE3AALDH1A1PDE4APDE4B | |
| SCHEMBL7308357 | 0.81 | PDE3B (0.36) | PDE3BPDE3AKDM4ECYP1A2CYP2C9 | |
| SCHEMBL7317951 | 0.80 | PDE3B (0.35) | PDE3BPDE3AMAPK1MEN1KMT2A | |
| SCHEMBL7303658 | 0.78 | PDE3B (0.39) | PDE3BPDE3AKDM4EMAPK1MEN1 | |
| SCHEMBL7314019 | 0.77 | PDE3B (0.38) | PDE3BPDE3AKDM4EALDH1A1MAPK1 | |
| SCHEMBL7313053 | 0.77 | PDE3B (0.38) | PDE3BPDE3AKDM4EMAPK1MEN1 | |
| SCHEMBL7309234 | 0.77 | PDE3B (0.35) | PDE3BPDE3AKDM4EALDH1A1MAPK1 | |
| SCHEMBL7313605 | 0.77 | PDE4A (0.40) | PDE3BPDE3AMEN1KMT2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |