Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318128 | 0.90 | PDE3B (0.39) | KMT2AALDH1A1MEN1CYP1A2CYP2C9 | |
| SCHEMBL7320482 | 0.86 | NPC1 (0.36) | KMT2AMEN1MAPTGAATSHR | |
| SCHEMBL7309234 | 0.85 | PDE3B (0.35) | KMT2AALDH1A1MEN1MAPTGAA | |
| SCHEMBL7321069 | 0.85 | PDE4A (0.43) | KMT2AMEN1MAPTGAATSHR | |
| SCHEMBL7318644 | 0.81 | PDE3B (0.35) | KMT2AALDH1A1MEN1CYP2C19MAPT | |
| SCHEMBL7311655 | 0.78 | PDE3B (0.38) | KMT2AALDH1A1MEN1MAPTGAA | |
| SCHEMBL7317651 | 0.78 | PDE3B (0.38) | KMT2AALDH1A1MEN1MAPTGAA | |
| SCHEMBL7320179 | 0.77 | PDE4A (0.38) | KMT2AALDH1A1MEN1CYP1A2CYP2C9 | |
| SCHEMBL7307661 | 0.76 | PDE4A (0.43) | KMT2AMEN1MAPTGAATSHR | |
| SCHEMBL7308357 | 0.76 | PDE3B (0.36) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |