Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.39 |
| ▸ | ANPEP | P15144 | 7/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.38 |
| ▸ | LAP3 | P28838 | 4/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318373 | 1.00 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| Hydrochloric Acid SCHEMBL8401309 | 0.98 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| Hydrochloric Acid SCHEMBL8401310 | 0.98 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL16540208 | 0.85 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL16540681 | 0.85 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL16540682 | 0.85 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL16049321 | 0.78 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL9100153 | 0.78 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL995721 | 0.78 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL24798069 | 0.76 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636117-A4 | METHOD OF ADMINISTERING PYRUVATE AND METHODS OF SYNTHESIZING PYRUVATE PRECURSORS. | ABBOTT LAB (US) | 1995-07-26 | — | — | EP | claimed |
| EP-0636117-A1 | USE OF PYRUVAMIDE AND SELECTED PYRUVYL-AMINO ACIDS | ABBOTT LABORATORIES (US) | 1995-02-01 | — | — | EP | claimed |
| WO-1993021147-A1 | METHOD OF ADMINISTERING PYRUVATE AND METHODS OF SYNTHESIZING PYRUVATE PRECURSORS | ABBOTT LABORATORIES (US) | 1993-10-28 | — | — | WO | claimed |
| EP-3632222-B1 | COMBINATION FOR REDUCING BLOOD LEAD | BEIJING RUIQIANJING SCIENCE AND TECH DEVELOPMENT CO LTD (CN) | 2024-06-19 | — | — | EP | disclosed |
| EP-3632221-B1 | COMPOSITION FOR IMPROVING INTESTINAL MICROECOLOGY AND PREVENTING CHRONIC DISEASE, BALANCED NUTRITIOUS FOOD, AND APPLICATION | BEIJING RUIQIANJING SCIENCE AND TECH DEVELOPMENT CO LTD (CN) | 2023-09-20 | — | — | EP | disclosed |
| EP-0636117-B1 | USE OF PYRUVAMIDE AND SELECTED PYRUVYL-AMINO ACIDS | STANKO RONALD T (US) | 1999-06-23 | — | — | EP | disclosed |
| US-5472980-A | Reducing insulin resistance in mammals with amino acid derivatives | ABBOTT LABORATORIES (US) | 1995-12-05 | — | — | US | disclosed |
| EP-0636117-A4 | METHOD OF ADMINISTERING PYRUVATE AND METHODS OF SYNTHESIZING PYRUVATE PRECURSORS. | ABBOTT LAB (US) | 1995-07-26 | — | — | EP | disclosed |
| EP-0636117-A1 | USE OF PYRUVAMIDE AND SELECTED PYRUVYL-AMINO ACIDS | ABBOTT LABORATORIES (US) | 1995-02-01 | — | — | EP | disclosed |
| US-5312985-A | Reaction of sodium pyruvate with thionyl chloride and oxalyl chloride to form pyruvyl chloride, then reaction with 1,1,1,3,3,3-hexamethyldisilazane and methanol to form pyruvamide | ABBOTT LABORATORIES (US) | 1994-05-17 | — | — | US | disclosed |
| US-5283260-A | Oral ingesting a pyruvyl-amino acid compound before a glucose tolerance test | ABBOTT LABORATORIES (US) | 1994-02-01 | — | — | US | disclosed |
| WO-1993021147-A1 | METHOD OF ADMINISTERING PYRUVATE AND METHODS OF SYNTHESIZING PYRUVATE PRECURSORS | ABBOTT LABORATORIES (US) | 1993-10-28 | — | — | WO | disclosed |
| US-5256697-A | Covalently linked pyruvyl-amino compound | ABBOTT LABORATORIES | 1993-10-26 | — | — | US | disclosed |
| US-5212163-A | Phosphonate dipeptide or tripeptide derivatives as collagenase inhibitors for treatment of connective tissue disorders | BEECHAM GROUP P.L.C. (GB) | 1993-05-18 | — | — | US | disclosed |
| EP-0527761-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | Beecham Group p.l.c. (GB) | 1993-02-24 | — | — | EP | disclosed |
| EP-0527764-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | Beecham Group p.l.c. (GB) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991015506-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-10-17 | — | — | WO | disclosed |
| WO-1991015507-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-10-17 | — | — | WO | disclosed |
| EP-0401963-A1 | Phosphonopeptides with collagenase inhibiting activity | Beecham Group p.l.c. (GB) | 1990-12-12 | — | — | EP | disclosed |