SCHEMBL16049321

SCHEMBL16049321

CC(C)C[C@H](N)C(=O)OOC(=O)[C@@H](N)CC(C)C

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.58
SLC1A3 P43003 3/20 0.45
SLC1A2 P43004 3/20 0.45
ANPEP P15144 7/20 0.42
RNPEP Q9H4A4 4/20 0.42
DNPEP Q9ULA0 2/20 0.42
LARS1 Q9P2J5 1/20 0.40
LAP3 P28838 4/20 0.39
ERAP1 Q9NZ08 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
ELANE P08246 1/20 0.39
SLC1A1 P43005 2/20 0.38
AAK1 Q2M2I8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18870463 0.89 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL995721 0.85 SLC7A5 (0.58) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL9100153 0.85 SLC7A5 (0.58) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL29564893 0.84 GABRP (0.48) SLC7A5SLC1A3SLC1A2SLC1A1
SCHEMBL24798069 0.83 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL76796 0.83 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL12345872 0.83 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL387310 0.83 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL700933 0.83 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL13144609 0.83 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2ANPEPRNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200325190-A1 Modification and Compositions of Human Secretoglobin Proteins APC RESEARCH ASSETS, LLC 2020-10-15 US claimed
US-20190337999-A1 Modification and Compositions of Human Secretoglobin Proteins APC RESEARCH ASSETS, LLC 2019-11-07 US claimed
US-10294285-B2 Modification and compositions of human secretoglobin proteins CLARASSANCE, INC. 2019-05-21 US claimed
US-20160362462-A1 Modification and Novel Compositions of Human Secretoglobin Proteins Therabron Therapeutics, Inc. (US) 2016-12-15 US claimed
US-9394349-B2 Modification and compositions of human secretoglobin proteins Therabron Therapeutics, Inc. (US) 2016-07-19 US claimed
CN-105744946-A Modification and Novel Compositions of Human Secretoglobin Proteins 希拉布朗治疗有限公司 2016-07-06 CN claimed
EP-2968449-A2 MODIFICATION AND NOVEL COMPOSITIONS OF HUMAN SECRETOGLOBIN PROTEINS Therabron Therapeutics, Inc. (US) 2016-01-20 EP claimed
WO-2014145368-A2 MODIFICATION AND NOVEL COMPOSITIONS OF HUMAN SECRETOGLOBIN PROTEINS CLARASSANCE, INC. (US) 2014-09-18 WO claimed
US-20140275477-A1 Modification and Compositions of Human Secretoglobin Proteins CLARASSANCE, INC. (US) 2014-09-18 US claimed
US-20210363203-A1 Modification and compositions of human secretoglobin proteins APC RESEARCH ASSETS, LLC 2021-11-25 US disclosed
US-20200325190-A1 Modification and Compositions of Human Secretoglobin Proteins APC RESEARCH ASSETS, LLC 2020-10-15 US disclosed
US-10676513-B2 Modification and compositions of human secretoglobin proteins APC RESEARCH ASSETS, LLC (US) 2020-06-09 US disclosed
US-20190337999-A1 Modification and Compositions of Human Secretoglobin Proteins APC RESEARCH ASSETS, LLC 2019-11-07 US disclosed
US-10294285-B2 Modification and compositions of human secretoglobin proteins CLARASSANCE, INC. 2019-05-21 US disclosed
US-20160362462-A1 Modification and Novel Compositions of Human Secretoglobin Proteins Therabron Therapeutics, Inc. (US) 2016-12-15 US disclosed
US-9394349-B2 Modification and compositions of human secretoglobin proteins Therabron Therapeutics, Inc. (US) 2016-07-19 US disclosed
CN-105744946-A Modification and Novel Compositions of Human Secretoglobin Proteins 希拉布朗治疗有限公司 2016-07-06 CN disclosed
EP-2968449-A2 MODIFICATION AND NOVEL COMPOSITIONS OF HUMAN SECRETOGLOBIN PROTEINS Therabron Therapeutics, Inc. (US) 2016-01-20 EP disclosed
WO-2014145368-A2 MODIFICATION AND NOVEL COMPOSITIONS OF HUMAN SECRETOGLOBIN PROTEINS CLARASSANCE, INC. (US) 2014-09-18 WO disclosed
US-20140275477-A1 Modification and Compositions of Human Secretoglobin Proteins CLARASSANCE, INC. (US) 2014-09-18 US disclosed