Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | DDX3X | O00571 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1899895 | 0.78 | NR1H2 (0.58) | PARP1DDX3XNPC1RAB9AADORA3 | |
| SCHEMBL7316537 | 0.77 | PARP1 (0.46) | PARP1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL647914 | 0.73 | HPGD (0.53) | GPR84ATMNPSR1HPGDSALDH1A1 | |
| SCHEMBL7318431 | 0.73 | PARP1 (0.56) | PARP1GPR84NPSR1ALDH1A1KDM4E | |
| SCHEMBL23646023 | 0.73 | ATM (0.50) | ATMNPSR1PDE5APDE3BPDE3A | |
| SCHEMBL7325204 | 0.73 | MAPT (0.41) | PARP1GPR84ATMALDH1A1KDM4E | |
| SCHEMBL26108539 | 0.71 | ADORA2A (0.47) | DDX3XNPC1RAB9AADORA2AADORA1 | |
| SCHEMBL9515033 | 0.71 | KDM4E (0.53) | PARP1GPR84ALDH1A1HPGDKDM4E | |
| SCHEMBL28330637 | 0.71 | MAPK14 (0.53) | GPR84PDE5APDE3BPDE3ADCTPP1 | |
| SCHEMBL7322860 | 0.71 | DCUN1D1 (0.56) | ATMNPSR1HPGDSALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071913-A | 2-(1H-TETRAZOL-5-YL)-4'-(AS-TRIAZIN-YLMETHYL)BIPHENYLS; CARDIOVASCULAR DISEASES, ESPECIALLY HYPERTENSION AND CONGESTIVE HEART FAILURE | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2000-06-06 | — | — | US | disclosed |