Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | NR1I3 | Q14994 | 5/20 | 0.36 |
| ▸ | ATP4A | P20648 | 2/20 | 0.35 |
| ▸ | ATP4B | P51164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7321620 | 0.99 | HRH3 (0.41) | HRH3MAPTNR1I3ATP4AATP4B | |
| SCHEMBL7674368 | 0.80 | NPC1 (0.49) | HRH3MAPT | |
| SCHEMBL7318463 | 0.80 | HRH3 (0.64) | HRH3ATP4AATP4B | |
| SCHEMBL7677823 | 0.80 | HRH3 (0.67) | HRH3MAPTGAAPOLBTP53 | |
| SCHEMBL10569536 | 0.80 | HRH3 (0.42) | HRH3MAPTGAAPOLB | |
| SCHEMBL7317802 | 0.79 | NR1I3 (0.40) | MAPTNR1I3GAAPOLBPTGS1 | |
| SCHEMBL7319647 | 0.78 | SMN1; SMN2 (0.56) | HRH3MAPTPOLBTP53 | |
| SCHEMBL10569141 | 0.78 | HRH3 (0.54) | HRH3 | |
| Hydrochloric Acid SCHEMBL7307729 | 0.78 | NPC1 (0.55) | HRH3MAPTPOLBTP53 | |
| SCHEMBL10569049 | 0.77 | HRH3 (0.42) | HRH3MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880824-A | CARDIOVASCULAR DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-11-14 | — | — | US | claimed |
| US-4880824-A | CARDIOVASCULAR DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-11-14 | — | — | US | disclosed |