⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930805 | 0.79 | ALDH1A1 (0.37) | — | |
| SCHEMBL792423 | 0.79 | — | — | |
| SCHEMBL6237757 | 0.79 | — | — | |
| SCHEMBL13360774 | 0.78 | ALDH1A1 (0.42) | — | |
| SCHEMBL7320291 | 0.78 | — | — | |
| SCHEMBL2143579 | 0.78 | ALDH1A1 (0.45) | — | |
| SCHEMBL5595896 | 0.78 | FFAR3 (0.45) | — | |
| SCHEMBL792518 | 0.78 | — | — | |
| SCHEMBL14182372 | 0.78 | TDP1 (0.45) | — | |
| SCHEMBL11310556 | 0.76 | TSHR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020127765-A1 | CRYSTALLINE PHOSPHATE SALTS | INTERVET INTERNATIONAL B.V. (NL) | 2020-06-25 | — | — | WO | disclosed |
| EP-2891650-B1 | METHOD FOR PRODUCING BIARYL COMPOUND | API CORP (JP) | 2018-08-01 | — | — | EP | disclosed |
| US-9624181-B2 | Method for producing biaryl compound | API CORPORATION (JP) | 2017-04-18 | — | — | US | disclosed |
| US-20150239853-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | API CORPORATION (JP) | 2015-08-27 | — | — | US | disclosed |
| EP-2891650-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | API Corporation (JP) | 2015-07-08 | — | — | EP | disclosed |
| US-20120201816-A1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-08-09 | — | — | US | disclosed |
| US-7169795-B2 | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors | BRISTOL MYERS SQUIBB COMPANY (US) | 2007-01-30 | — | — | US | disclosed |
| CN-1094742-A | Lattice with solventless coatings of improved wet scrub resistance | CRAY VALLEY SA (FR) | 1994-11-09 | — | — | CN | disclosed |
| US-5223387-A | Releasable cyan dye for diffusion transfer; self-development; colorfastness; hues; storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1993-06-29 | — | — | US | disclosed |
| EP-0263071-B1 | 2-Substituted-e-fused-[1,2,4]-triazolo[1,5-c] pyrimidines, pharmaceutical compositions, and uses thereof | CIBA-GEIGY AG (CH) | 1992-08-12 | — | — | EP | disclosed |
| US-4741988-A | Patterned polyimide film, a photosensitive polyamide acid derivative and an electrophoretic image-display cell | U.S. PHILIPS CORP. (US) | 1988-05-03 | — | — | US | disclosed |
| WO-1988002370-A1 | 2-SUBSTITUTED-E-FUSED-[1,2,4]TRIAZOLO[1,5-C]PYRIMIDINES PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | CIBA-GEIGY AG (CH) | 1988-04-07 | — | — | WO | disclosed |
| EP-0263071-A1 | 2-Substituted-e-fused-[1,2,4]-triazolo[1,5-c] pyrimidines, pharmaceutical compositions, and uses thereof | CIBA-GEIGY AG (CH) | 1988-04-06 | — | — | EP | disclosed |
| EP-0217748-A2 | 2-Substituted-e-fused-[1,2,4,]triazolo-[1,5-c]pyrimidines pharmaceutical compositions and uses thereof | CIBA-GEIGY AG (CH) | 1987-04-08 | — | — | EP | disclosed |
| EP-0202705-A1 | Patterned polyimide film, a photosensitive polyamide acid derivative and an electrophoretic image-display cell | Koninklijke Philips Electronics N.V. (NL) | 1986-11-26 | — | — | EP | disclosed |
| EP-0015773-B1 | N-(6-((ACYLAMINOACYLAMINO OR AMINOACYLAMINO)PHENYL) 1,2-DIHYDRO-2-OXONICOTINYL)PENICILLIN COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND COMPOSITIONS CONTAINING THEM | WARNER-LAMBERT COMPANY (US) | 1983-07-20 | — | — | EP | disclosed |
| US-4294958-A | Water-soluble salts of trimethylammonium derivatives of polyene macrolide antibiotics and the preparation thereof | POLITECHNIKA GDANSKA (PL) | 1981-10-13 | — | — | US | disclosed |
| US-4278681-A | N-/6-//ACYLAMINOACYLAMINO OR AMINOACYLAMINO/PHENYL/-1,2-DIHYDRO-2-OXONICOTINYL/PENICILLINS | WARNER-LAMBERT CO. (US) | 1981-07-14 | — | — | US | disclosed |
| EP-0015773-A2 | N-(6-((acylaminoacylamino or aminoacylamino)phenyl) 1,2-dihydro-2-oxonicotinyl)penicillin compounds, processes for their production and compositions containing them | WARNER-LAMBERT COMPANY (US) | 1980-09-17 | — | — | EP | disclosed |
| US-4203847-A | SOLVENT BATHS | MILLIPORE CORPORATION (US) | 1980-05-20 | — | — | US | disclosed |