Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068943 | 1.00 | PPARG (0.41) | PPARGPPARAKDM4EALDH1A1LMNA | |
| SCHEMBL27486346 | 0.87 | NR1H4 (0.41) | ALDH1A1LMNAHSP90AA1ELANEGRIN2D | |
| SCHEMBL7001546 | 0.86 | ELANE (0.55) | PPARGPPARAKDM4EALDH1A1LMNA | |
| SCHEMBL11239814 | 0.85 | MAPT (0.43) | KDM4ELMNAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL27497673 | 0.84 | TAS1R3 (0.47) | ALDH1A1LMNACYP2D6 | |
| SCHEMBL23493150 | 0.81 | ELANE (0.55) | ALDH1A1LMNAELANEGRIN2DGRIN3B | |
| SCHEMBL15679080 | 0.81 | ELANE (0.55) | ALDH1A1LMNAELANEGRIN2DGRIN3B | |
| SCHEMBL8895329 | 0.81 | TTR (0.38) | ALDH1A1LMNAELANEGRIN2DGRIN3B | |
| SCHEMBL6509969 | 0.80 | GRIN2D (0.53) | PPARALMNAELANEGRIN2DGRIN3B | |
| SCHEMBL2941688 | 0.80 | GRIN2D (0.53) | PPARALMNAELANEGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110506049-A | For combining the peptide ligand of MT1-MMP | BICYCLETX LTD | 2019-11-26 | — | — | CN | claimed |
| EP-0961779-A1 | SUBSTITUTED AMINO BICYCLIC-$g(b)-LACTAM PENAM AND CEPHAM DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS | SYNPHAR LABORATORIES INC. (CA) | 1999-12-08 | — | — | EP | claimed |
| WO-1998032766-A1 | SUBSTITUTED AMINO BICYCLIC-β-LACTAM PENAM AND CEPHAM DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS | SYNPHAR LABORATORIES INC. (US) | 1998-07-30 | — | — | WO | claimed |
| CN-110506049-A | For combining the peptide ligand of MT1-MMP | BICYCLETX LTD | 2019-11-26 | — | — | CN | disclosed |
| CN-106946748-B | Deliver method, compound, composition and the carrier of 3-APS | BHI有限合资公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-104379146-B | Inhibit the composition and method of varial polymerases | 拜奥克里斯特制药公司 | 2018-07-10 | — | — | CN | disclosed |
| CN-104284891-B | Conformationally constrained, fully synthetic macrocyclic compounds | 波利弗尔股份公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-105007928-B | For treating the synthesizing linear APELIN analogies of heart failure | 诺华股份有限公司 | 2018-03-20 | — | — | CN | disclosed |
| CN-106946748-A | Deliver method, compound, composition and the carrier of the propane sulfonic acid of 3 amino 1 | BHI有限合资公司 | 2017-07-14 | — | — | CN | disclosed |
| CN-106573073-A | FAP-activated therapeutics and uses related thereto | 塔夫茨大学信托人 | 2017-04-19 | — | — | CN | disclosed |
| CN-103787927-B | Deliver method, compound, compositionss and the carrier of 3 amino 1 propane sulfonic acid | BHI有限合资公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-104379146-A | Compositions and methods for inhibiting viral polymerase | BIOCRYST PHARM INC | 2015-02-25 | — | — | CN | disclosed |
| CN-1599577-A | Peptide-based multimeric targeted contrast media | EPIX MEDICAL INC (US) | 2005-03-23 | — | — | CN | disclosed |
| US-6232305-B1 | ANTICANCER AGENTS; BONE DISORDERS; ANTIARTHRITIC AGENTS; RESPIRATORY SYSTEM DISORDERS | NAEJA PHARMACEUTICAL INC. (CA) | 2001-05-15 | — | — | US | disclosed |
| EP-0961779-A1 | SUBSTITUTED AMINO BICYCLIC-$g(b)-LACTAM PENAM AND CEPHAM DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS | SYNPHAR LABORATORIES INC. (CA) | 1999-12-08 | — | — | EP | disclosed |
| WO-1998032766-A1 | SUBSTITUTED AMINO BICYCLIC-β-LACTAM PENAM AND CEPHAM DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS | SYNPHAR LABORATORIES INC. (US) | 1998-07-30 | — | — | WO | disclosed |