Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320312 | 0.85 | L3MBTL1 (0.39) | L3MBTL1MMEL1NOD2 | |
| SCHEMBL7312321 | 0.84 | MME (0.48) | L3MBTL1MMEL1 | |
| SCHEMBL7348558 | 0.84 | MME (0.48) | L3MBTL1MMEL1 | |
| SCHEMBL7314444 | 0.82 | TLR2 (0.39) | L3MBTL1 | |
| SCHEMBL7310277 | 0.80 | CYP3A4 (0.42) | L3MBTL1MMEL1NOD2 | |
| SCHEMBL7354164 | 0.80 | L3MBTL1 (0.46) | L3MBTL1MMEL1CTSLCTSSNOD2 | |
| SCHEMBL7322114 | 0.80 | L3MBTL1 (0.37) | L3MBTL1MMEL1CTSLCTSSNOD2 | |
| SCHEMBL7318799 | 0.80 | L3MBTL1 (0.41) | L3MBTL1MMEL1NOD2 | |
| SCHEMBL7311112 | 0.79 | L3MBTL1 (0.40) | L3MBTL1MMEL1NOD2KLKB1 | |
| SCHEMBL7348239 | 0.79 | L3MBTL1 (0.44) | L3MBTL1MMEL1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |