SCHEMBL7318705

SCHEMBL7318705

CN(C)C(CCl)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 8/20 0.50
ADRA2B P18089 2/20 0.50
ADRA2C P18825 2/20 0.50
ADRA1A P35348 2/20 0.50
SLC6A2 P23975 2/20 0.50
SLC6A4 P31645 2/20 0.50
SLC6A3 Q01959 2/20 0.50
HTR2A P28223 1/20 0.50
KCNH2 Q12809 1/20 0.50
SIGMAR1 Q99720 3/20 0.47
MAOB P27338 6/20 0.45
MAOA P21397 4/20 0.44
CYP1A2 P05177 2/20 0.44
ADRA2A P08913 1/20 0.44
SNCA P37840 1/20 0.44
CYP2D6 P10635 1/20 0.44
PKM P14618 1/20 0.44
TSHR P16473 1/20 0.44
OPRD1 P41143 6/20 0.44
TAAR1 Q96RJ0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7318710 1.00 OPRK1 (0.50) OPRK1ADRA2BADRA2CADRA1ASLC6A2
SCHEMBL7324807 1.00 OPRK1 (0.50) OPRK1ADRA2BADRA2CADRA1ASLC6A2
Hydrochloric Acid SCHEMBL27290669 0.98 OPRK1 (0.48) OPRK1ADRA2BADRA2CADRA1ASLC6A2
Hydrochloric Acid SCHEMBL27290671 0.98 OPRK1 (0.48) OPRK1ADRA2BADRA2CADRA1ASLC6A2
SCHEMBL42419 0.83 OPRK1 (0.50) OPRK1ADRA2BADRA2CADRA1ASLC6A2
SCHEMBL4676268 0.83 OPRK1 (0.50) OPRK1ADRA2BADRA2CADRA1ASLC6A2
Hydrochloric Acid SCHEMBL29408473 0.82 SLC6A2 (0.48) OPRK1ADRA2BADRA2CADRA1ASLC6A2
Hydrochloric Acid SCHEMBL29408495 0.82 SLC6A2 (0.48) OPRK1ADRA2BADRA2CADRA1ASLC6A2
Hydrochloric Acid SCHEMBL27557899 0.82 SLC6A2 (0.48) OPRK1ADRA2BADRA2CADRA1ASLC6A2
SCHEMBL9915838 0.81 OPRK1 (0.52) OPRK1ADRA2BADRA2CADRA1ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025070542-A1 MEMBER FOR SUPPRESSING FORMATION OF ICE NUCLEUS, SUPPRESSING FORMATION OF FROST, AND SUPPRESSING ACCRETION OF SNOW AND ICE 日本ペイント・サーフケミカルズ株式会社 2025-04-03 WO disclosed
WO-2025070541-A1 COATING COMPOSITION 国立大学法人京都大学 2025-04-03 WO disclosed
US-4902684-A Benzazepine and benzothiazepine derivatives E. R. SQUIBB & SONS, INC. (US) 1990-02-20 US disclosed
WO-1989012633-A1 BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES E.R. SQUIBB & SONS, INC. (US) 1989-12-28 WO disclosed