SCHEMBL7318734

SCHEMBL7318734

NC(=O)CCCC(Oc1cccc2c1N=C1NC(=O)C(CO)N1C2)N1CCCC2CCCCC21

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 8/20 0.39
PDE3A Q14432 8/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7306843 0.86 PDE3B (0.37) PDE3BPDE3A
SCHEMBL7319203 0.79 PDE3B (0.37) PDE3BPDE3A
SCHEMBL10754387 0.77 PDE3B (0.44) PDE3BPDE3A
SCHEMBL10374500 0.75 PDE3B (0.51) PDE3BPDE3A
SCHEMBL7320610 0.73 PDE3B (0.34) PDE3BPDE3A
SCHEMBL7309546 0.70 PDE3B (0.40) PDE3BPDE3A
SCHEMBL7321033 0.70 PDE3B (0.71) PDE3BPDE3A
SCHEMBL7310495 0.69 PDE3B (0.53) PDE3BPDE3A
SCHEMBL7315749 0.69 PDE3B (0.67) PDE3BPDE3A
SCHEMBL10375730 0.68 PDE3B (0.64) PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4670434-A ANTICOAGULANT, INOTROPIC AGENT SYNTEX (U.S.A.) INC. (US) 1987-06-02 US disclosed