Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 9/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 9/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304380 | 0.78 | PDE3B (0.36) | PDE3BPDE3A | |
| SCHEMBL10845675 | 0.73 | PDE3B (0.52) | PDE3BPDE3ALMNACYP1A2CYP3A4 | |
| SCHEMBL7306843 | 0.73 | PDE3B (0.37) | PDE3BPDE3A | |
| SCHEMBL10844852 | 0.72 | PDE3B (0.51) | PDE3BPDE3ALMNACYP1A2CYP3A4 | |
| SCHEMBL10844386 | 0.71 | PDE3B (0.50) | PDE3BPDE3ALMNACYP1A2CYP3A4 | |
| SCHEMBL10841625 | 0.71 | PDE3B (0.49) | PDE3BPDE3ALMNACYP1A2CYP3A4 | |
| SCHEMBL10844230 | 0.71 | PDE3B (0.49) | PDE3BPDE3ALMNACYP1A2CYP3A4 | |
| SCHEMBL10844784 | 0.71 | PDE3B (0.49) | PDE3BPDE3ALMNACYP1A2CYP3A4 | |
| SCHEMBL10842014 | 0.70 | PDE3B (0.47) | PDE3BPDE3ALMNACYP1A2CYP3A4 | |
| SCHEMBL7318734 | 0.70 | PDE3B (0.39) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |