Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 12/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.39 |
| ▸ | DPP4 | P27487 | 5/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | ARG1 | P05089 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321859 | 0.99 | DPP7 (0.39) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL7318606 | 0.87 | DPP7 (0.43) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL7327932 | 0.75 | DPP7 (0.38) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL5552493 | 0.75 | DPP8 (0.43) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL649164 | 0.75 | DPP8 (0.43) | DPP7DPP8DPP4DPP9FAP | |
| Water SCHEMBL3369508 | 0.74 | DPP7 (0.42) | DPP7DPP8DPP4DPP9FAP | |
| SCHEMBL10883512 | 0.72 | DPP7 (0.39) | DPP7DPP8DPP4DPP9 | |
| SCHEMBL10779843 | 0.71 | KMT2A (0.37) | DPP7DPP8DPP4DPP9FAP | |
| Methanesulfonamide SCHEMBL11097510 | 0.71 | DPP8 (0.39) | DPP7DPP8DPP9 | |
| SCHEMBL10784165 | 0.70 | DPP7 (0.36) | DPP7DPP8DPP4DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279750-B1 | AMINOACID DERIVATIVES AS ANTIHYPERTENSIVES | Asahi Breweries, Ltd. (JP) | 1993-01-20 | — | — | EP | claimed |
| EP-0279750-A2 | Aminoacid derivatives as antihypertensives | Asahi Breweries, Ltd. (JP) | 1988-08-24 | — | — | EP | claimed |
| EP-0279750-B1 | AMINOACID DERIVATIVES AS ANTIHYPERTENSIVES | Asahi Breweries, Ltd. (JP) | 1993-01-20 | — | — | EP | disclosed |