Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 10/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311541 | 0.91 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DMAOB | |
| SCHEMBL7311518 | 0.90 | ALDH1A1 (0.37) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7311440 | 0.86 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7319179 | 0.85 | LCK (0.36) | PDE4APDE4BPDE4CPDE4DLCK | |
| SCHEMBL7351296 | 0.85 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DLCK | |
| SCHEMBL7351300 | 0.77 | LCK (0.36) | PDE4APDE4BPDE4CPDE4DLCK | |
| SCHEMBL7311511 | 0.76 | ALDH1A1 (0.35) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7311535 | 0.76 | MAPT (0.37) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL7312716 | 0.75 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DITGB3 | |
| SCHEMBL7317727 | 0.75 | ALDH1A1 (0.37) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |