Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20876001 | 0.80 | RAB9A (0.56) | RAB9ANPC1TP53TSHRMAPT | |
| SCHEMBL7319228 | 0.79 | RAB9A (0.39) | RAB9ANPC1TP53TSHRMAPT | |
| SCHEMBL7312312 | 0.71 | FYN (0.43) | RAB9ANPC1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL9056407 | 0.65 | LSS (0.61) | RAB9ANPC1ALDH1A1MAPK1HDAC1 | |
| SCHEMBL7317298 | 0.65 | BACE1 (0.57) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL20893212 | 0.65 | RAB9A (0.55) | RAB9ANPC1TP53TSHRMAPT | |
| SCHEMBL11096825 | 0.65 | CYP3A4 (0.52) | RAB9ANPC1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL11093336 | 0.62 | KCNA3 (0.52) | SMN1; SMN2L3MBTL1CYP2D6GAAALDH1A1 | |
| SCHEMBL23246063 | 0.62 | HPGD (0.62) | RAB9ANPC1TSHRHTTMEN1 | |
| SCHEMBL29712390 | 0.62 | HPGD (0.62) | RAB9ANPC1TSHRHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880824-A | CARDIOVASCULAR DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-11-14 | — | — | US | disclosed |