SCHEMBL7319310

SCHEMBL7319310

O=C(O)C1(Cl)CC1c1cc(Cl)c(C2CCCCC2)c(Cl)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 7/20 0.34
PTGDR Q13258 4/20 0.34
KMO O15229 2/20 0.34
PTGER2 P43116 1/20 0.34
ACMSD Q8TDX5 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
PRKAB2 O43741 1/20 0.31
PRKAG1 P54619 1/20 0.31
PRKAA2 P54646 1/20 0.31
PRKAA1 Q13131 1/20 0.31
PRKAG3 Q9UGI9 1/20 0.31
PRKAG2 Q9UGJ0 1/20 0.31
PRKAB1 Q9Y478 1/20 0.31
CYP3A4 P08684 1/20 0.31
SERPINE1 P05121 1/20 0.31
CYP2D6 P10635 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7315850 0.82 PTGDR2 (0.40) PTGDR2PTGDRKMOPTGER2ACMSD
SCHEMBL28317670 0.80 CYP3A4 (0.31) NPC1RAB9ACYP3A4KMT2A
SCHEMBL7317859 0.79 HAO1 (0.44) KMOACMSDSMN1; SMN2NPC1RAB9A
SCHEMBL28190923 0.75 TPMT (0.38) KMT2A
SCHEMBL28190200 0.74 NPSR1 (0.43) KMONPC1RAB9ASLC6A2SLC6A4
SCHEMBL7346178 0.73 CYP3A4 (0.40) PTGDR2PTGDRKMOPTGER2ACMSD
SCHEMBL7313183 0.71 FFAR1 (0.41) KMOACMSD
SCHEMBL8579966 0.70 SLC6A2 (0.41) KMOACMSDCYP2D6SLC6A2SLC6A4
SCHEMBL7321511 0.70 SLC18A3 (0.40) PTGDR2PTGDRKMOPTGER2ACMSD
Hydrochloric Acid SCHEMBL7319313 0.70 FFAR1 (0.40) KMOACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6235791-B1 USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE SANOFI-SYNTHELABO (FR) 2001-05-22 US disclosed