Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315850 | 0.82 | PTGDR2 (0.40) | ACMSDKMO | |
| SCHEMBL7346178 | 0.81 | CYP3A4 (0.40) | ACMSDCYP3A4KMOCYP2C9 | |
| SCHEMBL28317778 | 0.80 | MAPK1 (0.45) | KMT2ACYP2C9MEN1BLM | |
| SCHEMBL3866422 | 0.79 | MAPK1 (0.47) | — | |
| SCHEMBL7319310 | 0.79 | PTGDR2 (0.34) | ACMSDKMT2AKDM4EGLAHTT | |
| SCHEMBL28316732 | 0.78 | LMNA (0.39) | KMT2ASMN1; SMN2L3MBTL1CYP2C9MEN1 | |
| SCHEMBL28876302 | 0.78 | LIG1 (0.44) | KMT2ATDP1CYP2C9BCL2L1MEN1 | |
| SCHEMBL7321511 | 0.77 | SLC18A3 (0.40) | ACMSDKMT2AHTTSMN1; SMN2KMO | |
| Hydrogen Peroxide SCHEMBL11391495 | 0.74 | HAO1 (0.55) | HAO1ACMSDKMT2AKDM4EGLA | |
| SCHEMBL28268441 | 0.73 | CA12 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235791-B1 | USING CIS N-CYCLOHEXYL-N-ETHYL(3-(3-CHLORO-CYCLOHEXYLPHENYL)ALLYL)AMINE | SANOFI-SYNTHELABO (FR) | 2001-05-22 | — | — | US | disclosed |