Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | COMT | P21964 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44284 | 0.77 | KDM4E (0.50) | KMT2ACOMTSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL20649339 | 0.75 | KMT2A (0.59) | KMT2ACOMTSMN1; SMN2KDM4EMGLL | |
| SCHEMBL20176617 | 0.75 | KMT2A (0.53) | KMT2ASMN1; SMN2KDM4EMGLLGSK3A | |
| SCHEMBL7266489 | 0.75 | KMT2A (0.48) | KMT2ACOMTSMN1; SMN2KDM4E | |
| SCHEMBL10434353 | 0.75 | KMT2A (0.53) | KMT2ACOMTSMN1; SMN2KDM4EMGLL | |
| SCHEMBL10472772 | 0.75 | BCHE (0.52) | KMT2ASMN1; SMN2KDM4ECYP3A4MEN1 | |
| SCHEMBL92862 | 0.75 | KMT2A (0.59) | KMT2ASMN1; SMN2KDM4EMGLLGSK3A | |
| SCHEMBL7316169 | 0.75 | KMT2A (0.69) | KMT2AKDM4EMEN1POLBALDH1A1 | |
| SCHEMBL9521015 | 0.74 | CYP3A4 (0.43) | KMT2ACOMTSMN1; SMN2KDM4EMGLL | |
| SCHEMBL30241908 | 0.73 | CYP2A6 (0.58) | CYP3A4GAAMAPK1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239391-B1 | 1,2,6-triphenyl-4(1H)-pyridinone and pyridinethione derivatives, production and uses thereof | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1994-03-02 | — | — | EP | disclosed |
| US-5254679-A | Containing a quaternized nitrogen | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-19 | — | — | US | disclosed |
| US-5246928-A | Cardiovascular disorders | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-09-21 | — | — | US | disclosed |
| US-5066653-A | Cardiovascular disorders; bronchodilators; phosphodiesterase inhibitors | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-19 | — | — | US | disclosed |
| US-5049558-A | Quaternized nitrogen-heterocycle substituted | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-09-17 | — | — | US | disclosed |
| EP-0164944-B1 | CEPHALOSPORIN DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-07-11 | — | — | EP | disclosed |
| US-4906628-A | N-phenylpyridone type III phosphodiesterases | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-03-06 | — | — | US | disclosed |
| US-4871751-A | 1,2,6-Triphenyl-4(1H)-pyridinone derivatives, and their use as fungicides | KUMAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |
| US-4757081-A | Agriculture, horticulture | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0239391-A2 | 1,2,6-triphenyl-4(1H)-pyridinone and pyridinethione derivatives, production and uses thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-30 | — | — | EP | disclosed |
| EP-0220044-A2 | 4(4-oxo-1,4-dihydropyridin-1-yl)phenyl derivatives | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-04-29 | — | — | EP | disclosed |
| EP-0164944-A1 | Cephalosporin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-12-18 | — | — | EP | disclosed |
| US-4083984-A | 1-Substituted phenyl-4(1H)-pyridinone hydrazones and composition therewith for treatment of coccidiosis | MERCK & CO., INC. (US) | 1978-04-11 | — | — | US | disclosed |