Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.64 |
| ▸ | CPA1 | P15085 | 2/20 | 0.62 |
| ▸ | CPB1 | P15086 | 1/20 | 0.62 |
| ▸ | CPA3 | P15088 | 1/20 | 0.62 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.62 |
| ▸ | MMP2 | P08253 | 12/20 | 0.57 |
| ▸ | MMP3 | P08254 | 4/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17537908 | 0.93 | GRIK1 (0.54) | GRIK1CPA1CPB1CPA3CPB2 | |
| SCHEMBL11311301 | 0.89 | CPA1 (0.67) | GRIK1CPA1CPB1CPA3CPB2 | |
| SCHEMBL9196227 | 0.89 | CPA1 (0.67) | GRIK1CPA1CPB1CPA3CPB2 | |
| SCHEMBL10734883 | 0.89 | CPA1 (0.67) | GRIK1CPA1CPB1CPA3CPB2 | |
| SCHEMBL1856639 | 0.89 | GRIK1 (0.72) | GRIK1CPA1CPA3CPB2MMP2 | |
| SCHEMBL1860416 | 0.85 | GRIK1 (0.68) | GRIK1CPA3CPB2MMP2MMP3 | |
| SCHEMBL7366093 | 0.85 | GRIK1 (0.59) | GRIK1CPA1CPB1CPA3CPB2 | |
| SCHEMBL7861733 | 0.85 | TSHR (0.66) | GRIK1MMP2MMP3 | |
| SCHEMBL17693397 | 0.85 | CA2 (0.50) | GRIK1CPA1CPB1CPA3CPB2 | |
| SCHEMBL17537904 | 0.85 | FOLH1 (0.61) | GRIK1CPA1CPB1CPA3CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561758-A2 | Method of preparing optically active homo-beta-amino acids | MONSANTO COMPANY (US) | 1993-09-22 | — | — | EP | disclosed |
| US-5229420-A | Renin inhibitor | G. D. SEARLE & CO. (US) | 1993-07-20 | — | — | US | disclosed |
| EP-0349921-A2 | Etheral n-terminal aminodiol amino acid derivatives as anti-hypertensive agents | G.D. Searle & Co. (US) | 1990-01-10 | — | — | EP | disclosed |