Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312995 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7313012 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7319717 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7326851 | 0.88 | HRH3 (0.51) | KDM4EALDH1A1MEN1KMT2AKCNH2 | |
| SCHEMBL7312730 | 0.87 | HRH3 (0.62) | KDM4EALDH1A1KCNH2HRH3MAPT | |
| SCHEMBL7326355 | 0.87 | HRH3 (0.62) | KDM4EALDH1A1KCNH2HRH3MAPT | |
| SCHEMBL7324138 | 0.87 | HRH3 (0.52) | KCNH2HRH3MAPTTP53CA12 | |
| SCHEMBL7350288 | 0.86 | HRH3 (0.63) | KDM4EALDH1A1KCNH2HRH3MAPT | |
| SCHEMBL7319729 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7313001 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |