Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.62 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.49 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | THRA | P10827 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312730 | 1.00 | HRH3 (0.62) | HRH3KCNH2HRH4CACNA1FBCHE | |
| SCHEMBL7350288 | 0.99 | HRH3 (0.63) | HRH3KCNH2HRH4CACNA1FBCHE | |
| SCHEMBL7324138 | 0.93 | HRH3 (0.52) | HRH3KCNH2HRH4CACNA1FBCHE | |
| SCHEMBL7326851 | 0.92 | HRH3 (0.51) | HRH3KCNH2MAPTTHRATHRB | |
| SCHEMBL7313012 | 0.87 | KDM4E (0.51) | HRH3KCNH2MAPTTHRATHRB | |
| SCHEMBL7312995 | 0.87 | KDM4E (0.51) | HRH3KCNH2MAPTTHRATHRB | |
| SCHEMBL7319735 | 0.87 | KDM4E (0.51) | HRH3KCNH2MAPTTHRATHRB | |
| SCHEMBL7319717 | 0.87 | KDM4E (0.51) | HRH3KCNH2MAPTTHRATHRB | |
| SCHEMBL6132534 | 0.86 | TP53 (0.50) | HRH3KCNH2MAPTTP53 | |
| SCHEMBL7326365 | 0.83 | HRH3 (0.64) | HRH3KCNH2HRH4CACNA1FBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |