Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 11/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11336728 | 0.80 | MEN1 (0.66) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL7317735 | 0.79 | MAPT (0.59) | MEN1KMT2AMAPTLMNAALOX15 | |
| SCHEMBL30612632 | 0.78 | MEN1 (0.64) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL4285418 | 0.78 | MEN1 (0.64) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL11449646 | 0.77 | MEN1 (0.62) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL21104415 | 0.77 | MEN1 (0.62) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL30612626 | 0.77 | MEN1 (0.62) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL22042882 | 0.77 | MEN1 (0.62) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL805061 | 0.77 | MEN1 (0.71) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL9447335 | 0.77 | MEN1 (0.62) | MEN1KMT2AMAPTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172896-A | ANTICONVULSANTS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1979-10-30 | — | — | US | disclosed |