Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317192 | 0.83 | MAPT (0.59) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL1272707 | 0.83 | LMNA (0.65) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL1272704 | 0.83 | MAPT (0.59) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL7306976 | 0.83 | NPC1 (0.59) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL7317185 | 0.81 | MAPT (0.58) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL2069593 | 0.80 | NPC1 (0.56) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL7319793 | 0.79 | MEN1 (0.56) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL11336715 | 0.76 | MAPT (0.51) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL622536 | 0.76 | NPC1 (0.70) | MAPTNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL2125044 | 0.76 | MAPT (0.70) | MAPTNPC1RAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172896-A | ANTICONVULSANTS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1979-10-30 | — | — | US | disclosed |