Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325015 | 0.91 | RAB9A (0.40) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL7355873 | 0.90 | RAB9A (0.46) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL7319181 | 0.89 | MAPT (0.41) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7322838 | 0.88 | SMN1; SMN2 (0.41) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL7322493 | 0.79 | SMN1; SMN2 (0.35) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL7322951 | 0.78 | NPC1 (0.38) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL7322920 | 0.78 | SMN1; SMN2 (0.34) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7322015 | 0.78 | NPC1 (0.37) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL7312044 | 0.77 | NPC1 (0.33) | NPC1RAB9APOLBKDM4ESMN1; SMN2 | |
| SCHEMBL7317468 | 0.76 | SMN1; SMN2 (0.35) | NPC1RAB9APOLBKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719145-A | FIBRINOGEN ANTAGONIST FOR TREATMENT OF THROMBOSIS, RESTENOSIS AFTER ANGIOPLASTY OR CORONARY RECANALIZATION; WATER SOLUBILITY, ORAL ADMINISTRATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-02-17 | — | — | US | disclosed |