Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.51 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319842 | 1.00 | MIF (0.51) | MIFSLC15A1EPHX1CSNK1EPOLB | |
| SCHEMBL7319847 | 1.00 | MIF (0.51) | MIFSLC15A1EPHX1CSNK1EPOLB | |
| SCHEMBL7578243 | 0.80 | MIF (0.59) | MIFPOLBKMT2AMEN1AGTR1 | |
| SCHEMBL9764695 | 0.80 | MIF (0.59) | MIFPOLBKMT2AMEN1AGTR1 | |
| SCHEMBL3285388 | 0.78 | MIF (0.53) | MIFEPHX1POLBPKML3MBTL1 | |
| SCHEMBL27502071 | 0.76 | EPHX1 (0.52) | SLC15A1EPHX1CSNK1EPKMALPI | |
| SCHEMBL22885996 | 0.74 | LAP3 (0.40) | SLC15A1EPHX1CSNK1EPKMALPI | |
| SCHEMBL15272327 | 0.74 | KMT2A (0.58) | MIFPOLBKMT2AMEN1AGTR1 | |
| SCHEMBL15272598 | 0.74 | KMT2A (0.58) | MIFPOLBKMT2AMEN1AGTR1 | |
| SCHEMBL11151822 | 0.74 | KMT2A (0.58) | MIFPOLBKMT2AMEN1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |