Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | EDNRB | P24530 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30281291 | 0.89 | PDK2 (0.50) | PDK2CYP3A4 | |
| SCHEMBL19039047 | 0.89 | PDK2 (0.50) | PDK2CYP3A4 | |
| SCHEMBL13165950 | 0.87 | PDK2 (0.50) | PDK2MDM2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13165953 | 0.85 | PDK2 (0.51) | PDK2MDM2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14970800 | 0.83 | PDK2 (0.45) | PDK2 | |
| SCHEMBL12938477 | 0.83 | PDK2 (0.45) | PDK2 | |
| SCHEMBL31576206 | 0.83 | PDK2 (0.45) | PDK2 | |
| SCHEMBL813078 | 0.82 | THRB (0.52) | PDK2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30345614 | 0.82 | THRB (0.52) | PDK2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21732768 | 0.82 | PDK2 (0.61) | PDK2CYP1A2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |